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http://purl.uniprot.org/citations/25657994 | http://www.w3.org/2000/01/rdf-schema#comment | "BRCA1-associated ATM activator-1 (BRAT1) was identified by our group as a DNA damage response (DDR) protein, which can bind with many DDR proteins and regulates their functions after DNA damage. However, previous study has also implicated BRAT1 as a regulator of cell growth and apoptosis. In this study, targeted gene deletion showed that BRAT1 is critical in stability and serum-induced expression of mTOR and downstream protein. Conditional deletion of BRAT1 of mouse embryonic fibroblasts suppressed serum-induced cell cycling progress. Our results suggest that BRAT1 is essential factor for PIKK signaling cascades."xsd:string |
http://purl.uniprot.org/citations/25657994 | http://purl.uniprot.org/core/author | "Ouchi T."xsd:string |
http://purl.uniprot.org/citations/25657994 | http://purl.uniprot.org/core/author | "Ouchi T."xsd:string |
http://purl.uniprot.org/citations/25657994 | http://purl.uniprot.org/core/author | "So E.Y."xsd:string |
http://purl.uniprot.org/citations/25657994 | http://purl.uniprot.org/core/author | "So E.Y."xsd:string |
http://purl.uniprot.org/citations/25657994 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/25657994 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/25657994 | http://purl.uniprot.org/core/name | "J. Cancer Biol. Res."xsd:string |
http://purl.uniprot.org/citations/25657994 | http://purl.uniprot.org/core/name | "J. Cancer Biol. Res."xsd:string |
http://purl.uniprot.org/citations/25657994 | http://purl.uniprot.org/core/title | "The potential role of BRCA1-associated ATM activator-1 (BRAT1) in regulation of mTOR."xsd:string |
http://purl.uniprot.org/citations/25657994 | http://purl.uniprot.org/core/title | "The potential role of BRCA1-associated ATM activator-1 (BRAT1) in regulation of mTOR."xsd:string |
http://purl.uniprot.org/citations/25657994 | http://purl.uniprot.org/core/volume | "1"xsd:string |
http://purl.uniprot.org/citations/25657994 | http://purl.uniprot.org/core/volume | "1"xsd:string |
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