http://purl.uniprot.org/citations/26223809 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/26223809 | http://www.w3.org/2000/01/rdf-schema#comment | "BackgroundPregnancy-associated plasma protein-A (PAPP-A) is discussed as a biomarker representing unstable plaques in coronary artery disease (CAD).MethodsIn this study 927 patients with CAD (534 with stable angina and 393 with acute coronary syndrome [ACS]) and 217 patients without CAD and measured PAPP-A levels were included. Follow-up for a median of 5 years was documented.ResultsRising quartiles of PAPP-A concentration had a higher cardiovascular mortality in the overall cohort of patients with CAD (p = 0.002) and the cohort with ACS (p = 0.01). Patients with suspected ACS below the LOD for troponin I but elevated PAPP-A levels had an increased cardiovascular mortality. A cut-off of 11.4 IU/l identified patients with a higher mortality during follow-up.ConclusionRising PAPP-A levels are prognostic in patients with CAD. PAPP-A levels were especially predictive in ACS patients with troponin below 10% CV of the 99 th percentile for cardiovascular mortality."xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.org/dc/terms/identifier | "doi:10.2217/bmm.15.41"xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/author | "Lackner K.J."xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/author | "Blankenberg S."xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/author | "Zeller T."xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/author | "Zengin E."xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/author | "Bickel C."xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/author | "Schnabel R.B."xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/author | "Rupprecht H.J."xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/author | "Westermann D."xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/author | "Sinning C."xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/name | "Biomark Med"xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/pages | "731-741"xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/title | "The utility of pregnancy-associated plasma protein A for determination of prognosis in a cohort of patients with coronary artery disease."xsd:string |
http://purl.uniprot.org/citations/26223809 | http://purl.uniprot.org/core/volume | "9"xsd:string |
http://purl.uniprot.org/citations/26223809 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/26223809 |
http://purl.uniprot.org/citations/26223809 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/26223809 |
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http://purl.uniprot.org/uniprot/#_Q13219-mappedCitation-26223809 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26223809 |
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http://purl.uniprot.org/uniprot/#_Q7Z613-mappedCitation-26223809 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/26223809 |