| http://purl.uniprot.org/citations/26286751 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26286751 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26286751 | http://www.w3.org/2000/01/rdf-schema#comment | "The C2 domain is one of the most diverse phospholipid-binding domains mediating cellular signaling. One group of C2-domain proteins are plant-specific and are characterized by their small sizes and simple structures. We have previously reported that a member of this group, OsGAP1, is able to alleviate salt stress and stimulate defense responses, and bind to both phospholipids and an unconventional G-protein, OsYchF1. Here we solved the crystal structure of OsGAP1 to a resolution of 1.63 Å. Using site-directed mutagenesis, we successfully differentiated between the clusters of surface residues that are required for binding to phospholipids versus OsYchF1, which, in turn, is critical for its role in stimulating defense responses. On the other hand, the ability to alleviate salt stress by OsGAP1 is dependent only on its ability to bind OsYchF1 and is independent of its phospholipid-binding activity."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m115.655639"xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m115.655639"xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Chye M.L."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Chye M.L."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Wong K.B."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Wong K.B."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Li K.P."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Li K.P."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Lam H.M."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Lam H.M."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Yu M.H."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Yu M.H."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Cheung M.Y."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Cheung M.Y."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Fong Y.H."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Fong Y.H."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Miao R."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Miao R."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Yung Y.L."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/author | "Yung Y.L."xsd:string |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |
| http://purl.uniprot.org/citations/26286751 | http://purl.uniprot.org/core/date | "2015"xsd:gYear |