| http://purl.uniprot.org/citations/26853939 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26853939 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/26853939 | http://www.w3.org/2000/01/rdf-schema#comment | "Insulin receptor (IR) signaling is critical to controlling nutrient uptake and metabolism. However, only a low-resolution (3.8 Å) structure currently exists for the IR ectodomain, with some segments ill-defined or unmodeled due to disorder. Here, we revise this structure using new diffraction data to 3.3 Å resolution that allow improved modeling of the N-linked glycans, the first and third fibronectin type III domains, and the insert domain. A novel haptic interactive molecular dynamics strategy was used to aid fitting to low-resolution electron density maps. The resulting model provides a foundation for investigation of structural transitions in IR upon ligand binding."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.str.2015.12.014"xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.str.2015.12.014"xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Lawrence M.C."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Lawrence M.C."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Smith B.J."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Smith B.J."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Whittaker J."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Whittaker J."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Ward C.W."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Ward C.W."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Weiss M.A."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Weiss M.A."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Margetts M.B."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Margetts M.B."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Croll T.I."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/author | "Croll T.I."xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/name | "Structure"xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/name | "Structure"xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/pages | "469-476"xsd:string |
| http://purl.uniprot.org/citations/26853939 | http://purl.uniprot.org/core/pages | "469-476"xsd:string |