RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/26871627http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/26871627http://www.w3.org/2000/01/rdf-schema#comment"The amyloid hypothesis for Alzheimer's disease (AD) posits a neuron-centric, linear cascade initiated by Aβ and leading to dementia. This direct causality is incompatible with clinical observations. We review evidence supporting a long, complex cellular phase consisting of feedback and feedforward responses of astrocytes, microglia, and vasculature. The field must incorporate this holistic view and take advantage of advances in single-cell approaches to resolve the critical junctures at which perturbations initially amenable to compensatory feedback transform into irreversible, progressive neurodegeneration."xsd:string
http://purl.uniprot.org/citations/26871627http://purl.org/dc/terms/identifier"doi:10.1016/j.cell.2015.12.056"xsd:string
http://purl.uniprot.org/citations/26871627http://purl.uniprot.org/core/author"De Strooper B."xsd:string
http://purl.uniprot.org/citations/26871627http://purl.uniprot.org/core/author"Karran E."xsd:string
http://purl.uniprot.org/citations/26871627http://purl.uniprot.org/core/date"2016"xsd:gYear
http://purl.uniprot.org/citations/26871627http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/26871627http://purl.uniprot.org/core/pages"603-615"xsd:string
http://purl.uniprot.org/citations/26871627http://purl.uniprot.org/core/title"The Cellular Phase of Alzheimer's Disease."xsd:string
http://purl.uniprot.org/citations/26871627http://purl.uniprot.org/core/volume"164"xsd:string
http://purl.uniprot.org/citations/26871627http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/26871627
http://purl.uniprot.org/citations/26871627http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/26871627
http://purl.uniprot.org/uniprot/P54764#attribution-4A090EC478C05C5007BB859402E4712Bhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/26871627
http://purl.uniprot.org/uniprot/O00264#attribution-4A090EC478C05C5007BB859402E4712Bhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/26871627
http://purl.uniprot.org/uniprot/P08138#attribution-4A090EC478C05C5007BB859402E4712Bhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/26871627