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http://purl.uniprot.org/citations/27892643http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/27892643http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/27892643http://www.w3.org/2000/01/rdf-schema#comment"Drought has a serious impact on agriculture worldwide. A plant's ability to adapt to rhizosphere drought stress requires reprogramming of root growth and development. Although physiological studies have documented the root adaption for tolerance to the drought stress, underlying molecular mechanisms is still incomplete, which is essential for crop engineering. Here, we identified OsNAC6-mediated root structural adaptations, including increased root number and root diameter, which enhanced drought tolerance. Multiyear drought field tests demonstrated that the grain yield of OsNAC6 root-specific overexpressing transgenic rice lines was less affected by drought stress than were nontransgenic controls. Genome-wide analyses of loss- and gain-of-function mutants revealed that OsNAC6 up-regulates the expression of direct target genes involved in membrane modification, nicotianamine (NA) biosynthesis, glutathione relocation, 3'-phophoadenosine 5'-phosphosulphate accumulation and glycosylation, which represent multiple drought tolerance pathways. Moreover, overexpression of NICOTIANAMINE SYNTHASE genes, direct targets of OsNAC6, promoted the accumulation of the metal chelator NA and, consequently, drought tolerance. Collectively, OsNAC6 orchestrates novel molecular drought tolerance mechanisms and has potential for the biotechnological development of high-yielding crops under water-limiting conditions."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.org/dc/terms/identifier"doi:10.1111/pbi.12673"xsd:string
http://purl.uniprot.org/citations/27892643http://purl.org/dc/terms/identifier"doi:10.1111/pbi.12673"xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Kim Y.S."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Kim Y.S."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Jang G."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Jang G."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Kim J.K."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Kim J.K."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Choi Y.D."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Choi Y.D."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Jeong J.S."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Jeong J.S."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Jung H."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Jung H."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Ha S.H."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Ha S.H."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Lee D.K."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Lee D.K."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Bang S.W."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Bang S.W."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Chung P.J."xsd:string
http://purl.uniprot.org/citations/27892643http://purl.uniprot.org/core/author"Chung P.J."xsd:string