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http://purl.uniprot.org/citations/2850496http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2850496http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2850496http://www.w3.org/2000/01/rdf-schema#comment"The structure of the human receptor for platelet-derived growth factor (PDGF) has been deduced through cDNA cloning. A 5.45-kilobase-pair cDNA clone predicts a 1,106-amino-acid polypeptide, including the cleavable signal sequence. The overall amino acid sequence similarity with the murine PDGF receptor is 85%. After transcription of the cDNA and translation in vitro, a PDGF receptor antiserum was used to immunoprecipitate a product of predicted size, which also could be phosphorylated in vitro. Stable introduction of the cDNA into Chinese hamster ovary (CHO) cells led to the expression of a 190-kilodalton component, which was immunoprecipitated by the PDGF receptor antiserum; this most probably represents the mature PDGF receptor. Binding assays with different 125I-labeled dimeric forms of PDGF A and B chains showed that the PDGF receptor expressed in CHO cells bound PDGF-BB and, to a lesser extent, PDGF-AB, but not PDGF-AA."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.org/dc/terms/identifier"doi:10.1128/mcb.8.8.3476-3486.1988"xsd:string
http://purl.uniprot.org/citations/2850496http://purl.org/dc/terms/identifier"doi:10.1128/mcb.8.8.3476-3486.1988"xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Betsholtz C."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Betsholtz C."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Oestman A."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Oestman A."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Heldin C.-H."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Heldin C.-H."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Moren A."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Moren A."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Eriksson A."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Eriksson A."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Claesson-Welsh L."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Claesson-Welsh L."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Ek B."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Ek B."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Severinsson L."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/author"Severinsson L."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/date"1988"xsd:gYear
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/date"1988"xsd:gYear
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/name"Mol. Cell. Biol."xsd:string
http://purl.uniprot.org/citations/2850496http://purl.uniprot.org/core/name"Mol. Cell. Biol."xsd:string