| http://purl.uniprot.org/citations/28543875 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28543875 | http://www.w3.org/2000/01/rdf-schema#comment | "Interferon-stimulated gene 15 (ISG15), a ubiquitin-like protein, is induced by type I INF. Although several groups have reported ISGylation of the HCV NS5A protein, it is still unclear whether ISGylation of NS5A has anti- or pro-viral effects in hepatitis C virus (HCV) infection. In the present study, the role of ISGylation-independent, unconjugated ISG15 in HCV infection was examined. Immunoprecipitation analyses revealed that ISG15 interacts specifically with NS5A domain I. ISG15 mutants lacking the C-terminal glycine residue that is essential for ISGylation still interacted with NS5A protein. Taken together, these results suggest that unconjugated ISG15 affects the functions of HCV NS5A through protein-protein interaction."xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://purl.org/dc/terms/identifier | "doi:10.1111/1348-0421.12493"xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://purl.uniprot.org/core/author | "Abe T."xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://purl.uniprot.org/core/author | "Matsuura Y."xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://purl.uniprot.org/core/author | "Deng L."xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://purl.uniprot.org/core/author | "Matsui C."xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://purl.uniprot.org/core/author | "Minami N."xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://purl.uniprot.org/core/author | "Fukuhara T."xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://purl.uniprot.org/core/author | "Shoji I."xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28543875 | http://purl.uniprot.org/core/name | "Microbiol Immunol"xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://purl.uniprot.org/core/pages | "287-292"xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://purl.uniprot.org/core/title | "Unconjugated interferon-stimulated gene 15 specifically interacts with the hepatitis C virus NS5A protein via domain I."xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://purl.uniprot.org/core/volume | "61"xsd:string |
| http://purl.uniprot.org/citations/28543875 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28543875 |
| http://purl.uniprot.org/citations/28543875 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/28543875 |
| http://purl.uniprot.org/uniprot/#_P05161-mappedCitation-28543875 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28543875 |
| http://purl.uniprot.org/uniprot/P05161 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/28543875 |