| http://purl.uniprot.org/citations/2982951 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2982951 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2982951 | http://www.w3.org/2000/01/rdf-schema#comment | "The gene for the HLA-A2 antigen has been cloned from the human lymphoblastoid cell line 721. Comparison of this sequence with the published sequence for HLA-A3 permits the examination of two alleles at the extremely polymorphic HLA-A locus. A high degree of sequence conservation was seen in both coding and noncoding DNA, 97.2% and 94.5%, respectively. Interestingly, the 3' untranslated region was the most conserved, with 99.5% homology. The polymorphism of the HLA-A antigens results from a high proportion of amino acid substitutions relative to the total nucleotide changes in exons 2 and 3. Unlike the clustered differences seen in this region on comparison of two H-2K alleles of mouse, nucleotide substitutions between the HLA-A2 and A3 alleles are evenly distributed. Substitutions at silent sites and within introns were used to calculate an intra-allelic divergence time of at least 10 to 15 million years for these two HLA-A alleles."xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/author | "Orr H.T."xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/author | "Orr H.T."xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/author | "Koller B.H."xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/author | "Koller B.H."xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/date | "1985"xsd:gYear |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/date | "1985"xsd:gYear |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/name | "J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/name | "J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/pages | "2727-2733"xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/pages | "2727-2733"xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/title | "Cloning and complete sequence of an HLA-A2 gene: analysis of two HLA-A alleles at the nucleotide level."xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/title | "Cloning and complete sequence of an HLA-A2 gene: analysis of two HLA-A alleles at the nucleotide level."xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/volume | "134"xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://purl.uniprot.org/core/volume | "134"xsd:string |
| http://purl.uniprot.org/citations/2982951 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2982951 |
| http://purl.uniprot.org/citations/2982951 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2982951 |
| http://purl.uniprot.org/citations/2982951 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2982951 |
| http://purl.uniprot.org/citations/2982951 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2982951 |
| http://purl.uniprot.org/uniprot/P04439 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2982951 |
| http://purl.uniprot.org/uniprot/P04439#attribution-8F16356D8F37EC434AB466F91E026530 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/2982951 |
| http://purl.uniprot.org/uniprot/#_P04439-citation-2982951 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/2982951 |