| http://purl.uniprot.org/citations/30820467 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30820467 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/30820467 | http://www.w3.org/2000/01/rdf-schema#comment | "Shrimp nodaviruses, including Penaeus vannamei (PvNV) and Macrobrachium rosenbergii nodaviruses (MrNV), cause white-tail disease in shrimps, with high mortality. The viral capsid structure determines viral assembly and host specificity during infections. Here, we show cryo-EM structures of T = 3 and T = 1 PvNV-like particles (PvNV-LPs), crystal structures of the protrusion-domains (P-domains) of PvNV and MrNV, and the crystal structure of the ∆N-ARM-PvNV shell-domain (S-domain) in T = 1 subviral particles. The capsid protein of PvNV reveals five domains: the P-domain with a new jelly-roll structure forming cuboid-like spikes; the jelly-roll S-domain with two calcium ions; the linker between the S- and P-domains exhibiting new cross and parallel conformations; the N-arm interacting with nucleotides organized along icosahedral two-fold axes; and a disordered region comprising the basic N-terminal arginine-rich motif (N-ARM) interacting with RNA. The N-ARM controls T = 3 and T = 1 assemblies. Increasing the N/C-termini flexibility leads to particle polymorphism. Linker flexibility may influence the dimeric-spike arrangement."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.org/dc/terms/identifier | "doi:10.1038/s42003-019-0311-z"xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.org/dc/terms/identifier | "doi:10.1038/s42003-019-0311-z"xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Chan S.I."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Chan S.I."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Chen C.J."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Chen C.J."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Chuankhayan P."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Chuankhayan P."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Huang Y.C."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Huang Y.C."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Nakagawa A."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Nakagawa A."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Miyazaki N."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Miyazaki N."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Yoshimura M."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Yoshimura M."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Iwasaki K."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Iwasaki K."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Guan H.H."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Guan H.H."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Lin C.C."xsd:string |
| http://purl.uniprot.org/citations/30820467 | http://purl.uniprot.org/core/author | "Lin C.C."xsd:string |