| http://purl.uniprot.org/citations/3103856 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3103856 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3103856 | http://www.w3.org/2000/01/rdf-schema#comment | "DNA clones encoding the 3 mouse neurofilament (NF) genes have been isolated by cross-hybridization with a previously described NF-L cDNA probe from the rat. Screening of a lambda gt10 cDNA library prepared from mouse brain RNA led to the cloning of an NF-L cDNA of 2.0 kb that spans the entire coding region of 541 amino acids and of an NF-M cDNA that covers 219 amino acids from the internal alpha-helical region and the carboxy-terminal domains of the protein. These cDNA clones were used as probes to screen mouse genomic libraries, and cosmid clones containing both NF-L and NF-M sequences were isolated as well as overlapping cosmids containing the NF-H gene. This strongly suggests that the 3 neurofilament genes are organised in a cluster and derived by gene duplication of a common ancestral gene. RNA blot analyses using specific DNA probes for each of the genes indicate that NF mRNAs are differentially expressed during brain development. The NF-L and NF-M mRNAs are detected early in the embryonal brain, with a progressive increase in their levels during development, while the NF-H mRNA is barely detectable at embryonal stages and accumulates later in the postnatal brain."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.org/dc/terms/identifier | "doi:10.1016/0169-328x(86)90030-6"xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.org/dc/terms/identifier | "doi:10.1016/0169-328x(86)90030-6"xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/author | "Meyer D."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/author | "Meyer D."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/author | "Grosveld F."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/author | "Grosveld F."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/author | "Hurst J."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/author | "Hurst J."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/author | "Julien J.-P."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/author | "Julien J.-P."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/author | "Flavell D."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/author | "Flavell D."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/date | "1986"xsd:gYear |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/date | "1986"xsd:gYear |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/name | "Brain Res."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/name | "Brain Res."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/pages | "243-250"xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/pages | "243-250"xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/title | "Cloning and developmental expression of the murine neurofilament gene family."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/title | "Cloning and developmental expression of the murine neurofilament gene family."xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/volume | "387"xsd:string |
| http://purl.uniprot.org/citations/3103856 | http://purl.uniprot.org/core/volume | "387"xsd:string |