| http://purl.uniprot.org/citations/3220103 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3220103 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3220103 | http://www.w3.org/2000/01/rdf-schema#comment | "The mouse CTLA-4 gene has been shown to code for an activated lymphocyte-associated sequence belonging to the Ig gene superfamily. We now report on the molecular cloning and study of the human corresponding gene isolated from a genomic library and designated Hu-CTLA-4. The Hu-CTLA-4 gene exists as a single copy per human haploid genome and maps to band q33 of chromosome 2. It comprises 3 exons notwithstanding the leader sequence. The first exon encodes a V-like domain of 116 amino acids, the second one a hydrophobic putative transmembrane region of 37 amino acids and the third one a 34 amino acid putative cytoplasmic domain. Whereas the overall homology between the human and murine CTLA-4 proteins is 76%, there is, remarkably, a complete identity of their cytoplasmic domains. This complete interspecies conservation comes in support of an important role for this domain in CTLA-4 function."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.org/dc/terms/identifier | "doi:10.1002/eji.1830181206"xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.org/dc/terms/identifier | "doi:10.1002/eji.1830181206"xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/author | "Golstein P."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/author | "Golstein P."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/author | "Mattei M.-G."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/author | "Mattei M.-G."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/author | "Dariavach P."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/author | "Dariavach P."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/author | "Lefranc M.-P."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/author | "Lefranc M.-P."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/name | "Eur. J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/name | "Eur. J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/pages | "1901-1905"xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/pages | "1901-1905"xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/title | "Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/title | "Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains."xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/volume | "18"xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://purl.uniprot.org/core/volume | "18"xsd:string |
| http://purl.uniprot.org/citations/3220103 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3220103 |
| http://purl.uniprot.org/citations/3220103 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3220103 |