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http://purl.uniprot.org/citations/3322813http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3322813http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3322813http://www.w3.org/2000/01/rdf-schema#comment"Human glioblastoma cells secrete a peptide, termed glioblastoma-derived T cell suppressor factor (G-TsF), which has suppressive effects on interleukin-2-dependent T cell growth. As shown here, complementary DNA for G-TsF reveals that G-TsF shares 71% amino acid homology with transforming growth factor-beta (TGF-beta). In analogy to TGF-beta it is apparently synthesized as the carboxy-terminal end of a precursor polypeptide which undergoes proteolytic cleavage to yield the 112 amino-acid-long mature form of G-TsF. Comparison of the amino-terminal sequence of G-TsF with that of porcine TGF-beta 2 and bovine cartilage-inducing factor B shows complete homology, which indicates that we have cloned the human analogue of these factors. It is tempting to consider a role for G-TsF in tumor growth where it may enhance tumor cell proliferation in an autocrine way and/or reduce immunosurveillance of tumor development."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.org/dc/terms/identifier"doi:10.1002/j.1460-2075.1987.tb02700.x"xsd:string
http://purl.uniprot.org/citations/3322813http://purl.org/dc/terms/identifier"doi:10.1002/j.1460-2075.1987.tb02700.x"xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Fontana A."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Fontana A."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Haendler B."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Haendler B."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"de Martin R."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"de Martin R."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Hofer E."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Hofer E."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Seifert J.M."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Seifert J.M."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Wrann M."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Wrann M."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Hofer-Warbinek R."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Hofer-Warbinek R."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Bodmer S."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Bodmer S."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Gaugitsch H."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Gaugitsch H."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Schluesener H."xsd:string
http://purl.uniprot.org/citations/3322813http://purl.uniprot.org/core/author"Schluesener H."xsd:string