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http://purl.uniprot.org/citations/6091049http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/6091049http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/6091049http://www.w3.org/2000/01/rdf-schema#comment"As a first step in our studies of functionally rearranged K genes of man we cloned the germline JK-CK region from placenta DNA employing a mouse JK clone as hybridization probe. Subclones of the human JK-CK region were then used to characterize and clone the rearranged K genes of the lymphoid cell lines Walker and Daudi. The Walker cell line contains one rearranged and one germline K allele (K+,KO; ref. 1). Only one K gene was found in Daudi cells (K+). Restriction mapping and DNA sequencing showed, that the rearranged K genes from both cell lines are closely related. These features make the two cell lines particularly suitable for studies on the chromatin structure of K light chain genes. The 5' flanks of the two genes (388 bp) are identical while there is a 12% divergence between the VK gene segments themselves. This situation may reflect somatic mutation processes and/or gene conversion like events."xsd:string
http://purl.uniprot.org/citations/6091049http://purl.org/dc/terms/identifier"doi:10.1093/nar/12.18.6995"xsd:string
http://purl.uniprot.org/citations/6091049http://purl.org/dc/terms/identifier"doi:10.1093/nar/12.18.6995"xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/author"Zachau H.G."xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/author"Zachau H.G."xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/author"Combriato G."xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/author"Combriato G."xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/author"Klobeck H.G."xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/author"Klobeck H.G."xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/date"1984"xsd:gYear
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/date"1984"xsd:gYear
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/name"Nucleic Acids Res."xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/name"Nucleic Acids Res."xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/pages"6995-7006"xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/pages"6995-7006"xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/title"Immunoglobulin genes of the kappa light chain type from two human lymphoid cell lines are closely related."xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/title"Immunoglobulin genes of the kappa light chain type from two human lymphoid cell lines are closely related."xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/volume"12"xsd:string
http://purl.uniprot.org/citations/6091049http://purl.uniprot.org/core/volume"12"xsd:string
http://purl.uniprot.org/citations/6091049http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/6091049
http://purl.uniprot.org/citations/6091049http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/6091049
http://purl.uniprot.org/citations/6091049http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/6091049
http://purl.uniprot.org/citations/6091049http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/6091049