| http://purl.uniprot.org/citations/6865944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/6865944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/6865944 | http://www.w3.org/2000/01/rdf-schema#comment | "The sequence of a human beta-tubulin cDNA clone (D beta-1) is described; our data revealed 95.6% homology compared with the sequence of a human beta-tubulin processed pseudogene derived by reverse transcription of a processed mRNA (Wilde et al., Nature [London] 297:83-84, 1982). However, the amino acid sequence encoded by this cDNA showed less homology with pig and chicken beta-tubulin sequences than the latter did to each other, with major divergence within the 15 carboxy-terminal amino acids. On the other hand, an independently isolated, functionally expressed genomic human beta-tubulin sequence (5 beta) possessed a very high degree of homology with chicken and pig beta-tubulins in this region. Thus, human cells appear to contain two distinct beta-tubulin isotypes. Both the intact beta-tubulin cDNA clone and a subclone containing only the 3' untranslated region detected two mRNA species in HeLa cells; these mRNAs were 1.8 and 2.6 kilobases long and were present in about equal amounts. Two independently subcloned probes constructed from the 3' untranslated region of the 5 beta genomic sequence also detected a 2.6-kilobase beta-tubulin mRNA. However, the 3'-untranslated-region probes from the cDNA clone and the genomic sequence did not cross-hybridize. Thus, at least two human beta-tubulin genes, each specifying a distinct isotype, are expressed in HeLa cells, and the 2.6-kilobase mRNA band is a composite of at least two comigrating beta-tubulin mRNAs."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.3.5.854-862.1983"xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.3.5.854-862.1983"xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/author | "Cowan N.J."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/author | "Cowan N.J."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/author | "Hall J.L."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/author | "Hall J.L."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/author | "Lewis S.A."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/author | "Lewis S.A."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/author | "Dobner P.R."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/author | "Dobner P.R."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/author | "Dudley L."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/author | "Dudley L."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/date | "1983"xsd:gYear |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/date | "1983"xsd:gYear |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/pages | "854-862"xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/pages | "854-862"xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/title | "Identification of two human beta-tubulin isotypes."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/title | "Identification of two human beta-tubulin isotypes."xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/volume | "3"xsd:string |
| http://purl.uniprot.org/citations/6865944 | http://purl.uniprot.org/core/volume | "3"xsd:string |