http://purl.uniprot.org/citations/7713498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/7713498 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/7713498 | http://www.w3.org/2000/01/rdf-schema#comment | "Phosphatidylinositol (PI) 3-kinase is a heterodimeric enzyme comprising a 110-kDa catalytic subunit and an 85-kDa regulatory subunit that binds to tyrosine phosphopeptide sites linked directly or indirectly to receptors serving diverse signal functions. Knowledge of the structure and function of PI 3-kinase was greatly advanced by the purification, cDNA cloning, and subsequent expression of the bovine enzyme. Here the cloning of the cDNA for the human p110 alpha subunit of PI 3-kinase (PIK3CA), encoding a protein 99% identical to the bovine p110, and of its gene in YAC is described. The chromosomal localization of the gene for PIK3CA is shown to be at 3q21-qter as determined using somatic cell hybrids. In situ hybridization performed using Alu-PCR from the YAC DNA located the gene in 3q26.3."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.org/dc/terms/identifier | "doi:10.1006/geno.1994.1655"xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.org/dc/terms/identifier | "doi:10.1006/geno.1994.1655"xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Volinia S."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Volinia S."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Nizetic D."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Nizetic D."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Rocchi M."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Rocchi M."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Waterfield M."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Waterfield M."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Antonacci R."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Antonacci R."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Ormondroyd E."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Ormondroyd E."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Hiles I."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/author | "Hiles I."xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/pages | "472-477"xsd:string |
http://purl.uniprot.org/citations/7713498 | http://purl.uniprot.org/core/pages | "472-477"xsd:string |