| http://purl.uniprot.org/citations/7743522 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7743522 | http://www.w3.org/2000/01/rdf-schema#comment | "Mouse malignant T-lymphoma CS-21 cells undergo apoptotic cell death in vitro in the absence of lymph node stromal cells but escape apoptosis and proliferate when they are attached to CA-12 stromal cells. A monoclonal antibody raised against CS-21 cell surface molecules (MCS-5) recognized a M(r) 168,000 protein, inhibited binding of CS-21 cells to CA-12 stromal cells, and suppressed apoptosis in CS-21 cells. To identify the M(r) 168,000 protein, we purified it with MCS-5 affinity chromatography and ion exchange chromatography. Partial amino acid sequences of the purified M(r) 168,000 protein were identical to those of CD45, a transmembrane tyrosine phosphatase. The purified protein possessed tyrosine phosphatase activity and was recognized by an anti-CD45 monoclonal antibody. The M(r) 168,000 protein was identified as CD45. To determine the CD45 isoform, we cloned the CD45 gene from the cDNA library of CS-21. Sixteen of 18 clones encoded CD45RO (CD45 lacking exons 4, 5, and 6), and the remainder lacked exons 4, 5, 6, and 7. Like MCS-5, an anti-CD45 monoclonal antibody, also inhibited binding of CS-21 cells to CA-12 cells and suppressed apoptosis in CS-21 cells. Our present results indicate that CD45RO expressed on CS-21 cells mediates adhesion to CA-12 cells and suppression of apoptosis."xsd:string |
| http://purl.uniprot.org/citations/7743522 | http://purl.uniprot.org/core/author | "Fujita N."xsd:string |
| http://purl.uniprot.org/citations/7743522 | http://purl.uniprot.org/core/author | "Lee S.H."xsd:string |
| http://purl.uniprot.org/citations/7743522 | http://purl.uniprot.org/core/author | "Tsuruo T."xsd:string |
| http://purl.uniprot.org/citations/7743522 | http://purl.uniprot.org/core/author | "Naito M."xsd:string |
| http://purl.uniprot.org/citations/7743522 | http://purl.uniprot.org/core/author | "Hanaoka K."xsd:string |
| http://purl.uniprot.org/citations/7743522 | http://purl.uniprot.org/core/author | "Seimiya H."xsd:string |
| http://purl.uniprot.org/citations/7743522 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7743522 | http://purl.uniprot.org/core/name | "Cancer Res"xsd:string |
| http://purl.uniprot.org/citations/7743522 | http://purl.uniprot.org/core/pages | "2186-2190"xsd:string |
| http://purl.uniprot.org/citations/7743522 | http://purl.uniprot.org/core/title | "Involvement of CD45 in adhesion and suppression of apoptosis of mouse malignant T-lymphoma cells."xsd:string |
| http://purl.uniprot.org/citations/7743522 | http://purl.uniprot.org/core/volume | "55"xsd:string |
| http://purl.uniprot.org/citations/7743522 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7743522 |
| http://purl.uniprot.org/citations/7743522 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7743522 |
| http://purl.uniprot.org/uniprot/P06800#attribution-73481EA654BB52B39F8CBE1DC556EFAE | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/7743522 |
| http://purl.uniprot.org/uniprot/P06800#attribution-871B7E1F57101CD1FCB66B7C9BDF998B | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/7743522 |
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| http://purl.uniprot.org/uniprot/#_A0A0A6YXM4-mappedCitation-7743522 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7743522 |
| http://purl.uniprot.org/uniprot/#_A1E2H6-mappedCitation-7743522 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7743522 |
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| http://purl.uniprot.org/uniprot/#_P06800-mappedCitation-7743522 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7743522 |
| http://purl.uniprot.org/uniprot/#_Q5XFY7-mappedCitation-7743522 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7743522 |
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| http://purl.uniprot.org/uniprot/#_Q8C6Q7-mappedCitation-7743522 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7743522 |