| http://purl.uniprot.org/citations/7775445 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7775445 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7775445 | http://www.w3.org/2000/01/rdf-schema#comment | "Interleukin (IL)-13 elicits a subset of the biological activities of the related IL-4. The basis of this functional similarity is that their specific cell-surface receptors (called IL-13R and IL-4R) are distinct, yet are complex and share a common subunit(s). The IL-4R primary binding subunit (called IL-4R alpha) does not by itself bind IL-13. We show that the ability of IL-13 to partially compete for IL-4 binding to some human cell types depended on co-expression of IL-4R and IL-13R. However, IL-13 binding was always associated with IL-4 binding. Hyper-expression of IL-4R alpha on cells expressing both IL-4R and IL-13R decreased their binding affinity for IL-4, abrogated the ability of IL-13 to compete for IL-4 binding, and yet had no effect on IL-13R properties. Anti-human IL-4R alpha monoclonal antibodies which blocked the biological function and binding of IL-4 also blocked the function and binding of IL-13. These data show that IL-4R alpha is a secondary component of IL-13R."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.23.13869"xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.23.13869"xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Zurawski G."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Zurawski G."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Zurawski S.M."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Zurawski S.M."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Banchereau J."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Banchereau J."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Bidaud C."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Bidaud C."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "McKenzie A.N."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "McKenzie A.N."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Chomarat P."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Chomarat P."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Djossou O."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Djossou O."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Miossec P."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/author | "Miossec P."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/7775445 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |