| http://purl.uniprot.org/citations/7806582 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7806582 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7806582 | http://www.w3.org/2000/01/rdf-schema#comment | "beta-Catenin is involved in the formation of adherens junctions of mammalian epithelia. It interacts with the cell adhesion molecule E-cadherin and also with the tumor suppressor gene product APC, and the Drosophila homologue of beta-catenin, armadillo, mediates morphogenetic signals. We demonstrate here that E-cadherin and APC directly compete for binding to the internal, armadillo-like repeats of beta-catenin; the NH2-terminal domain of beta-catenin mediates the interaction of the alternative E-cadherin and APC complexes to the cytoskeleton by binding to alpha-catenin. Plakoglobin (gamma-catenin), which is structurally related to beta-catenin, mediates identical interactions. We thus show that the APC tumor suppressor gene product forms strikingly similar associations as found in cell junctions and suggest that beta-catenin and plakoglobin are central regulators of cell adhesion, cytoskeletal interaction, and tumor suppression."xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.127.6.2061"xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.127.6.2061"xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/author | "Behrens J."xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/author | "Behrens J."xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/author | "Birchmeier W."xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/author | "Birchmeier W."xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/author | "Huelsken J."xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/author | "Huelsken J."xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/name | "J. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/name | "J. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/pages | "2061-2069"xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/pages | "2061-2069"xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/title | "E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton."xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/title | "E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton."xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/volume | "127"xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://purl.uniprot.org/core/volume | "127"xsd:string |
| http://purl.uniprot.org/citations/7806582 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7806582 |
| http://purl.uniprot.org/citations/7806582 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7806582 |
| http://purl.uniprot.org/citations/7806582 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7806582 |
| http://purl.uniprot.org/citations/7806582 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7806582 |