http://purl.uniprot.org/citations/7836469 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/7836469 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/7836469 | http://www.w3.org/2000/01/rdf-schema#comment | "We have characterized a new ankyrin gene, expressed in brain and other tissues, that is subject to extensive tissue-specific alternative mRNA processing. The full-length polypeptide has a molecular mass of 480 kDa and includes a predicted globular head domain, with membrane- and spectrin-binding activities, as well as an extended "tail" domain. We term this gene ankyrinG based on its giant size and general expression. Two brain-specific isoforms of 480 kDa and 270 kDa were identified that contain a unique stretch of sequence highly enriched in serine and threonine residues immediately following the globular head domain. Antibodies against the serine-rich domain and spectrin-binding domain revealed labeling of nodes of Ranvier and axonal initial segments. Ankyrin-binding proteins also known to be localized in these specialized membrane domains include the voltage-dependent sodium channel, the sodium/potassium ATPase, sodium/calcium exchanger, and members of the neurofascin/L1 family of cell adhesion molecules. The neural-specific ankyrinG polypeptides are candidates to participate in maintenance/targeting of ion channels and cell adhesion molecules to nodes of Ranvier and axonal initial segments."xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.5.2352"xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.5.2352"xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/author | "Bennett V."xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/author | "Bennett V."xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/author | "Lambert S."xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/author | "Lambert S."xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/author | "Kordeli E."xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/author | "Kordeli E."xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/pages | "2352-2359"xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/pages | "2352-2359"xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/title | "AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier."xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/title | "AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier."xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/volume | "270"xsd:string |
http://purl.uniprot.org/citations/7836469 | http://purl.uniprot.org/core/volume | "270"xsd:string |
http://purl.uniprot.org/citations/7836469 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7836469 |
http://purl.uniprot.org/citations/7836469 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7836469 |
http://purl.uniprot.org/citations/7836469 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7836469 |
http://purl.uniprot.org/citations/7836469 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7836469 |