http://purl.uniprot.org/citations/7929060 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/7929060 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/7929060 | http://www.w3.org/2000/01/rdf-schema#comment | "A novel cytoplasmic protein tyrosine phosphatase (PTP), PTPL1, was identified and cloned using a polymerase chain reaction-based approach. Overlapping cDNA clones encompass an open reading frame of 7398 base pairs, predicting a protein of 2466 amino acid residues with a molecular mass of 275 kDa. PTPL1 has a wide tissue distribution, a 9.5-kilobase transcript being expressed in most tissues. Peptide antisera against PTPL1 specifically precipitate a protein with an apparent mass of 250 kDa. PTPL1 has a PTP domain located in the COOH terminus, and the protein was shown to dephosphorylate 32P-labeled myelin basic protein. In the non-enzymatic part of PTPL1, three different structural motifs can be identified. Two of these are often found in proteins at the interface between the plasma membrane and the cytoskeleton, i.e. a 300-amino acid domain with similarity to the band 4.1 superfamily, and a region consisting of five GLGF repeats, an 80-amino acid repeat found in a variety of cytoskeleton-associated proteins. In addition to these structures PTPL1 has a region that fulfills the criteria for a leucine zipper motif. PTPL1 is the hitherto largest PTP identified and the only one known which contains a leucine zipper motif."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)51050-x"xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)51050-x"xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/author | "Heldin C.-H."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/author | "Heldin C.-H."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/author | "Saras J."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/author | "Saras J."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/author | "Gonez L.J."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/author | "Gonez L.J."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/author | "Claesson-Welsh L."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/author | "Claesson-Welsh L."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/pages | "24082-24089"xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/pages | "24082-24089"xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/title | "Cloning and characterization of PTPL1, a protein tyrosine phosphatase with similarities to cytoskeletal-associated proteins."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/title | "Cloning and characterization of PTPL1, a protein tyrosine phosphatase with similarities to cytoskeletal-associated proteins."xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/volume | "269"xsd:string |
http://purl.uniprot.org/citations/7929060 | http://purl.uniprot.org/core/volume | "269"xsd:string |
http://purl.uniprot.org/citations/7929060 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7929060 |
http://purl.uniprot.org/citations/7929060 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7929060 |