| http://purl.uniprot.org/citations/7945238 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7945238 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7945238 | http://www.w3.org/2000/01/rdf-schema#comment | "It has previously been reported that two kinds of human gastric adenocarcinoma cell lines (STKM-1 and MKN28) secrete a trypsin-like enzyme. In this study, four molecular forms of the enzyme (26, 25, 24 and 23 kDa on non-reducing SDS/PAGE) were purified from the serum-free conditioned medium of STKM-1 cells. Analysis of N-terminal amino acid sequences showed that the 26 kDa protein was a two-chain form of trypsinogen 1 which had been produced by proteolytic cleavage of the Arg107-Val108 bond of trypsinogen 1, and the 24 kDa protein was the one-chain form of trypsinogen 1. The 25 and 23 kDa proteins were the activated forms of the two-chain and one-chain trypsinogen 1 respectively. Isoelectric focusing gave pI values of 6.3 and 6.6 for the 26 kDa two-chain form and the 24 kDa one-chain form of trypsinogen 1 respectively. Comparison of the proteolytic activities indicated that the one-chain trypsin 1 had amidolytic activity about four times higher than that of the two-chain enzyme."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.org/dc/terms/identifier | "doi:10.1042/bj3030187"xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.org/dc/terms/identifier | "doi:10.1042/bj3030187"xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/author | "Nagashima Y."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/author | "Nagashima Y."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/author | "Umeda M."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/author | "Umeda M."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/author | "Miyazaki K."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/author | "Miyazaki K."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/author | "Koshikawa N."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/author | "Koshikawa N."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/author | "Yasumitsu H."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/author | "Yasumitsu H."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/name | "Biochem. J."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/name | "Biochem. J."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/pages | "187-190"xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/pages | "187-190"xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/title | "Identification of one- and two-chain forms of trypsinogen 1 produced by a human gastric adenocarcinoma cell line."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/title | "Identification of one- and two-chain forms of trypsinogen 1 produced by a human gastric adenocarcinoma cell line."xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/volume | "303"xsd:string |
| http://purl.uniprot.org/citations/7945238 | http://purl.uniprot.org/core/volume | "303"xsd:string |