| http://purl.uniprot.org/citations/7961848 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7961848 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7961848 | http://www.w3.org/2000/01/rdf-schema#comment | "Phosphatidylinositol (PtdIns) 4-kinase catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Here we report the first mammalian cDNA clone of a PtdIns 4-kinase (named PI4K alpha). The 2.6-kb cDNA encodes a protein of 854 amino acids that is highly homologous to the recently cloned yeast PtdIns 4-kinase STT4 and is also homologous to a second yeast PtdIns 4-kinase, PIK1. PI4K alpha has more distant sequence homology to the catalytic domains of mammalian and yeast PtdIns 3-kinases and to the yeast Tor family of proteins. It also has a region of similarity to pleckstrin homology domains and a potential ankyrin repeat. Cross-hybridizing messages were detected in all human tissues investigated. The enzymatic properties of the protein expressed in insect cells are characteristic of type II PtdIns 4-kinases (activated by detergent and inhibited by adenosine), and PI4K alpha is recognized by an antibody specific for type II PtdIns 4-kinases."xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)61989-7"xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)61989-7"xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/author | "Cantley L.C."xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/author | "Cantley L.C."xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/author | "Wong K."xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/author | "Wong K."xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/pages | "28878-28884"xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/pages | "28878-28884"xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/title | "Cloning and characterization of a human phosphatidylinositol 4-kinase."xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/title | "Cloning and characterization of a human phosphatidylinositol 4-kinase."xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/volume | "269"xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://purl.uniprot.org/core/volume | "269"xsd:string |
| http://purl.uniprot.org/citations/7961848 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7961848 |
| http://purl.uniprot.org/citations/7961848 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7961848 |
| http://purl.uniprot.org/citations/7961848 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7961848 |
| http://purl.uniprot.org/citations/7961848 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7961848 |
| http://purl.uniprot.org/uniprot/P42356 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/7961848 |
| http://purl.uniprot.org/uniprot/P42356#attribution-214AFB630444E7D066942549CCC93554 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/7961848 |