| http://purl.uniprot.org/citations/8048567 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8048567 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8048567 | http://www.w3.org/2000/01/rdf-schema#comment | "The cDNA coding for the human renal isoform of the Na+/Ca2+ exchanger was cloned from a human embryonic kidney cell line (HEK 293) using a polymerase chain reaction strategy. It was found by sequence analysis that the cDNA encoded for a human kidney isoform of the Na+/Ca2+ exchanger. The kidney isoform is nearly identical to the human cardiac Na+/Ca2+ exchanger except for a segment of amino acids within the predicted cytoplasmic loop region of the molecule. Within this region, the kidney isoform contains a deletion of 36 amino acids, as well as a segment of 33 amino acids that is only 33% identical to the equivalent region of the cardiac exchanger. The cDNA was then tested for function by expression in insect cells. We constructed a recombinant baculovirus containing renal Na+/Ca2+ exchanger cDNA under control of the polyhedrin promoter. High levels of expression and Na+/Ca2+ exchange activity were found in Sf9 insect cells infected with the recombinant virus. Our results indicate that human kidney expresses a functional and alternatively spliced variant of the human cardiac Na+/Ca2+ exchanger."xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.org/dc/terms/identifier | "doi:10.1152/ajprenal.1994.267.1.f70"xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.org/dc/terms/identifier | "doi:10.1152/ajprenal.1994.267.1.f70"xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/author | "Clarke D.M."xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/author | "Clarke D.M."xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/author | "Loo T.W."xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/author | "Loo T.W."xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/name | "Am. J. Physiol."xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/name | "Am. J. Physiol."xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/pages | "F70-F74"xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/pages | "F70-F74"xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/title | "Functional expression of human renal Na+/Ca2+ exchanger in insect cells."xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/title | "Functional expression of human renal Na+/Ca2+ exchanger in insect cells."xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/volume | "267"xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://purl.uniprot.org/core/volume | "267"xsd:string |
| http://purl.uniprot.org/citations/8048567 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8048567 |
| http://purl.uniprot.org/citations/8048567 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8048567 |
| http://purl.uniprot.org/citations/8048567 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8048567 |
| http://purl.uniprot.org/citations/8048567 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8048567 |
| http://purl.uniprot.org/uniprot/P32418 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/8048567 |
| http://purl.uniprot.org/uniprot/#_kb.P32418_up.isolatedFrom_tissue.249 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/8048567 |