http://purl.uniprot.org/citations/8183892 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8183892 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8183892 | http://www.w3.org/2000/01/rdf-schema#comment | "The HLA-G monomorphic, nonclassical class I gene encodes the major histocompatibility complex (MHC) molecule, which is the only MHC antigen expressed on cytotrophoblast cells of placenta. In this work, we have investigated expression of the HLA-G gene in fetal tissues and adult peripheral blood cells by using a sensitive hot-start reverse transcriptase PCR technique. PCR amplification with HLA-G primers specific for exon 3 has enabled us to demonstrate an alternatively spliced form of HLA-G mRNA present in fetal first trimester trophoblasts and lacking exon 4 (HLA-G.3-5). This low abundance transcript (approximately 1:200) in comparison to full-length mRNA may encode the protein that excludes the alpha 3 domain and by conformational changes may present a different ability to bind to peptides. Moreover, expression of the HLA-G transcript was found in adult peripheral lymphocytes and equally in B- and T-cell populations. These results are discussed in the context of the fetal-maternal relationship presented by HLA-G gene products."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.91.10.4209"xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.91.10.4209"xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/author | "Moreau P."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/author | "Moreau P."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/author | "Kirszenbaum M."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/author | "Kirszenbaum M."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/author | "Dausset J."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/author | "Dausset J."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/author | "Carosella E."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/author | "Carosella E."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/author | "Gluckman E."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/author | "Gluckman E."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/pages | "4209-4213"xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/pages | "4209-4213"xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/title | "An alternatively spliced form of HLA-G mRNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/title | "An alternatively spliced form of HLA-G mRNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes."xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/volume | "91"xsd:string |
http://purl.uniprot.org/citations/8183892 | http://purl.uniprot.org/core/volume | "91"xsd:string |