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http://purl.uniprot.org/citations/8183892http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8183892http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8183892http://www.w3.org/2000/01/rdf-schema#comment"The HLA-G monomorphic, nonclassical class I gene encodes the major histocompatibility complex (MHC) molecule, which is the only MHC antigen expressed on cytotrophoblast cells of placenta. In this work, we have investigated expression of the HLA-G gene in fetal tissues and adult peripheral blood cells by using a sensitive hot-start reverse transcriptase PCR technique. PCR amplification with HLA-G primers specific for exon 3 has enabled us to demonstrate an alternatively spliced form of HLA-G mRNA present in fetal first trimester trophoblasts and lacking exon 4 (HLA-G.3-5). This low abundance transcript (approximately 1:200) in comparison to full-length mRNA may encode the protein that excludes the alpha 3 domain and by conformational changes may present a different ability to bind to peptides. Moreover, expression of the HLA-G transcript was found in adult peripheral lymphocytes and equally in B- and T-cell populations. These results are discussed in the context of the fetal-maternal relationship presented by HLA-G gene products."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.org/dc/terms/identifier"doi:10.1073/pnas.91.10.4209"xsd:string
http://purl.uniprot.org/citations/8183892http://purl.org/dc/terms/identifier"doi:10.1073/pnas.91.10.4209"xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/author"Moreau P."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/author"Moreau P."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/author"Kirszenbaum M."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/author"Kirszenbaum M."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/author"Dausset J."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/author"Dausset J."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/author"Carosella E."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/author"Carosella E."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/author"Gluckman E."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/author"Gluckman E."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/pages"4209-4213"xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/pages"4209-4213"xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/title"An alternatively spliced form of HLA-G mRNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/title"An alternatively spliced form of HLA-G mRNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes."xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/volume"91"xsd:string
http://purl.uniprot.org/citations/8183892http://purl.uniprot.org/core/volume"91"xsd:string