http://purl.uniprot.org/citations/8187069 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8187069 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8187069 | http://www.w3.org/2000/01/rdf-schema#comment | "The t(16;21)(p11;q22) translocation is a recurrent chromosomal abnormality found in several types of myeloid leukemia. We have previously demonstrated that the breakpoints of this translocation are clustered in a specific intron of the ERG gene on chromosome 21, which has recently been reported to be involved in Ewing's sarcoma. We show here that the TLS/FUS gene on chromosome 16 is fused with the ERG gene to produce the TLS/FUS-ERG chimeric transcript by this translocation. The TLS/FUS gene has been identified as a translocated gene in myxoid liposarcoma by the t(12;16)(q13;p11) translocation and encodes an RNA-binding protein that is highly homologous to the product of the EWS gene involved in Ewing's sarcoma. Thus, the TLS/FUS-ERG gene fusion in t(16;21) leukemia is predicted to produce a protein that is very similar to the EWS-ERG chimeric protein responsible for Ewing's sarcoma."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/author | "Hayashi Y."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/author | "Hayashi Y."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/author | "Shimizu K."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/author | "Shimizu K."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/author | "Ohki M."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/author | "Ohki M."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/author | "Ichikawa H."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/author | "Ichikawa H."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/name | "Cancer Res."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/name | "Cancer Res."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/pages | "2865-2868"xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/pages | "2865-2868"xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/title | "An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/title | "An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation."xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/volume | "54"xsd:string |
http://purl.uniprot.org/citations/8187069 | http://purl.uniprot.org/core/volume | "54"xsd:string |
http://purl.uniprot.org/citations/8187069 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8187069 |
http://purl.uniprot.org/citations/8187069 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8187069 |
http://purl.uniprot.org/citations/8187069 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8187069 |
http://purl.uniprot.org/citations/8187069 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8187069 |