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http://purl.uniprot.org/citations/8187069http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8187069http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8187069http://www.w3.org/2000/01/rdf-schema#comment"The t(16;21)(p11;q22) translocation is a recurrent chromosomal abnormality found in several types of myeloid leukemia. We have previously demonstrated that the breakpoints of this translocation are clustered in a specific intron of the ERG gene on chromosome 21, which has recently been reported to be involved in Ewing's sarcoma. We show here that the TLS/FUS gene on chromosome 16 is fused with the ERG gene to produce the TLS/FUS-ERG chimeric transcript by this translocation. The TLS/FUS gene has been identified as a translocated gene in myxoid liposarcoma by the t(12;16)(q13;p11) translocation and encodes an RNA-binding protein that is highly homologous to the product of the EWS gene involved in Ewing's sarcoma. Thus, the TLS/FUS-ERG gene fusion in t(16;21) leukemia is predicted to produce a protein that is very similar to the EWS-ERG chimeric protein responsible for Ewing's sarcoma."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/author"Hayashi Y."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/author"Hayashi Y."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/author"Shimizu K."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/author"Shimizu K."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/author"Ohki M."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/author"Ohki M."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/author"Ichikawa H."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/author"Ichikawa H."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/name"Cancer Res."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/name"Cancer Res."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/pages"2865-2868"xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/pages"2865-2868"xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/title"An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/title"An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation."xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/volume"54"xsd:string
http://purl.uniprot.org/citations/8187069http://purl.uniprot.org/core/volume"54"xsd:string
http://purl.uniprot.org/citations/8187069http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8187069
http://purl.uniprot.org/citations/8187069http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8187069
http://purl.uniprot.org/citations/8187069http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8187069
http://purl.uniprot.org/citations/8187069http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8187069