| http://purl.uniprot.org/citations/8208605 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8208605 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8208605 | http://www.w3.org/2000/01/rdf-schema#comment | "A set of genes (SWI1, SWI2/SNF2, SWI3, SNF5 and SNF6) in Saccharomyces cerevisiae are required for transcription of a variety of yeast genes. It was recently reported that the mammalian glucocorticoid receptor failed to activate transcription when transiently expressed in swi1-, swi2- or swi3-yeast strains. We report here that two highly related human cDNAs, hSNF2 alpha and -beta, encode amino acid sequences homologous to both the yeast SWI2/SNF2 and the Drosophila brahma. Similar to their yeast and Drosophila counterparts, both human cDNAs contain helicase motifs, a bromodomain, a highly charged C-terminal sequence and an N-terminal sequence rich in proline, glutamine and glycine. Tissue distribution of the mRNAs varied slightly. Transcriptional activation by the estrogen receptor and the retinoic acid receptor was enhanced by co-expression of either hSNF2 cDNA. No enhancement was observed for promoters which do not respond to nuclear receptors. We suggest that global transcriptional coactivators equivalent to the yeast SWI/SNF complex exist in mammalian cells."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/22.10.1815"xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/22.10.1815"xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/author | "Kato H."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/author | "Kato H."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/author | "Muramatsu M."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/author | "Muramatsu M."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/author | "Nomoto A."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/author | "Nomoto A."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/author | "Chiba H."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/author | "Chiba H."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/name | "Nucleic Acids Res."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/name | "Nucleic Acids Res."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/pages | "1815-1820"xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/pages | "1815-1820"xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/title | "Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/title | "Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor."xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/volume | "22"xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://purl.uniprot.org/core/volume | "22"xsd:string |
| http://purl.uniprot.org/citations/8208605 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8208605 |
| http://purl.uniprot.org/citations/8208605 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8208605 |