| http://purl.uniprot.org/citations/8226976 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8226976 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8226976 | http://www.w3.org/2000/01/rdf-schema#comment | "The mouse Kv1-5 K+ channel cDNA has been cloned from heart. This channel was highly expressed in heart and, to a lesser extent, in other tissues, including brain and thymus. Two alternatively spliced isoforms were found. The longer form encoded a 602-amino acid protein, while in the short form (Kv1-5 delta 5'), the first 200 amino acids lying upstream the transmembrane segment S1 were deleted. RNase protection experiments showed that both Kv1-5 mRNA isoforms are present in the mouse tissues examined, the longer form being predominant. The short mRNA (Kv1-5 delta 5') arose by an unusual splicing event within the exonic sequence. An additional short cDNA clone (Kv1-5 delta 3') that codes for a carboxyl-terminal truncated protein has been isolated. The gene coding sequence contained a single exon and has been mapped on human chromosome 12 (p13) and on mouse chromosome 6 (band F). Expression in Xenopus oocytes revealed that the long (Kv1-5) and the amino-terminal deleted (Kv1-5 delta 5') isoforms elicited similar K+ currents with a drastically decreased efficacy for Kv1-5 delta 5'. The carboxyl-terminal truncated Kv1-5 delta 3' clone was not functional but inhibited the expression of the long isoform."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(20)80523-7"xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(20)80523-7"xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Lazdunski M."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Lazdunski M."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Mattei M.-G."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Mattei M.-G."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Waldmann R."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Waldmann R."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Lesage F."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Lesage F."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Attali B."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Attali B."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Barhanin J."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Barhanin J."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Guillemare E."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Guillemare E."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Hugnot J.-P."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Hugnot J.-P."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Honore E."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Honore E."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Ziliani P."xsd:string |
| http://purl.uniprot.org/citations/8226976 | http://purl.uniprot.org/core/author | "Ziliani P."xsd:string |