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http://purl.uniprot.org/citations/8242616http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8242616http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8242616http://www.w3.org/2000/01/rdf-schema#comment"Reciprocal chromosome translocations involving 11q23 are frequently associated with acute leukemias, with the t(4;11) translocation predominating among acute lymphoblastic leukemias, and the t(9;11), t(11;19) and t(6;11) translocations most common among acute myeloid leukemias. In each of these translocations the ALL-1 gene, located at 11q23 and constituting the human homologue of Drosophila trithorax, fuses to a specific gene on the partner chromosome to produce a chimeric protein. Here we report the cloning and the characterization of the partner gene from chromosome 6 (AF-6). AF-6 is expressed in a variety of cell types and encodes a protein of 1612 amino acids. The protein contains short stretches rich in prolines, charged amino acids, serines, or glutamines. In addition, the AF-6 protein contains the GLGF motif shared with several proteins of vertebrates and invertebrates thought to be involved in signal transduction at special cell-cell junctions."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Gu Y."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Gu Y."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Nakamura T."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Nakamura T."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Miyazaki Y."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Miyazaki Y."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Saito H."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Saito H."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Huebner K."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Huebner K."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Canaani E."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Canaani E."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Croce C.M."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Croce C.M."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Gale R.P."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Gale R.P."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Prasad R."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Prasad R."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Alder H."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Alder H."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Canaani O."xsd:string
http://purl.uniprot.org/citations/8242616http://purl.uniprot.org/core/author"Canaani O."xsd:string