RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/8253383http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8253383http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8253383http://www.w3.org/2000/01/rdf-schema#comment"The adenovirus E1A proteins form complexes with a group of cellular proteins, including a protein of 130 kD. E1A-associated p130 was purified through coimmunoprecipitation with E1A, and sequence data from four tryptic peptides was obtained. Oligonucleotides derived from the peptide sequences were used to clone a 4.85-kb cDNA. The cDNA contained an 1139-amino-acid open reading frame with homology to the retinoblastoma protein and E1A-associated p107 but was more closely related to p107. In vitro-translated p130 bound to E1A, and anti-p130 antibodies detected p130 in immunoblots of E1A immunoprecipitates. p130 was also detected in immunoprecipitates of cyclins A and E and was an efficient substrate in vitro for kinase activities associated with these cyclins. The p130 gene mapped to chromosome 16q12.2-13, a region that undergoes allelic loss in several types of tumors, including hepatocellular, prostate, and breast carcinomas."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.org/dc/terms/identifier"doi:10.1101/gad.7.12a.2366"xsd:string
http://purl.uniprot.org/citations/8253383http://purl.org/dc/terms/identifier"doi:10.1101/gad.7.12a.2366"xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/author"Li Y."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/author"Li Y."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/author"Duncan A.M.V."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/author"Duncan A.M.V."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/author"Whyte P."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/author"Whyte P."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/author"Graham C."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/author"Graham C."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/author"Lacy S."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/author"Lacy S."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/name"Genes Dev."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/name"Genes Dev."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/pages"2366-2377"xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/pages"2366-2377"xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/title"The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/title"The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E."xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/volume"7"xsd:string
http://purl.uniprot.org/citations/8253383http://purl.uniprot.org/core/volume"7"xsd:string