http://purl.uniprot.org/citations/8270638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8270638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8270638 | http://www.w3.org/2000/01/rdf-schema#comment | "R-cadherin was originally identified as a chicken cadherin expressed by the retina. Here, we describe the identification of a mouse homologue of R-cadherin. We isolated mouse cDNAs encoding a cadherin with 94% identity in amino acid sequence to the chicken R-cadherin, and defined this molecule as mouse R-cadherin. L cells transfected with the mouse R-cadherin cDNA acquired a cadherin-mediated cell-cell adhesiveness as found for other cadherins. To examine the binding specificity of mouse R-cadherin, L cells expressing this cadherin (mRL) were mixed with L cells expressing chicken R-cadherin (cRL), mouse N-cadherin (mNL), mouse E-cadherin (mEL) and mouse P-cadherin (mPL). While mRL cells randomly intermixed with cRL cells, those cells aggregated separately from mEL or mPL cells. Mixing of mRL with mNL cells gave an intermediate result; that is, they formed both separate and chimeric aggregates, suggesting that R- and N-cadherin can interact with each other although each has a preference to bind to its own type. Similar properties were previously found for chicken R-cadherin. Thus, the cell binding specificity of R-cadherin is entirely conserved between the two species, suggesting a conserved role for this protein in morphogenesis. We also located the mouse R-cadherin gene to chromosome 2."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.org/dc/terms/identifier | "doi:10.1242/jcs.106.1.401"xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.org/dc/terms/identifier | "doi:10.1242/jcs.106.1.401"xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Inoue T."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Inoue T."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Takeichi M."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Takeichi M."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Matsunami H."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Matsunami H."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Copeland N.G."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Copeland N.G."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Jenkins N.A."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Jenkins N.A."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Gilbert D."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Gilbert D."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Miyatani S."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/author | "Miyatani S."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/name | "J. Cell Sci."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/name | "J. Cell Sci."xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/pages | "401-409"xsd:string |
http://purl.uniprot.org/citations/8270638 | http://purl.uniprot.org/core/pages | "401-409"xsd:string |