| http://purl.uniprot.org/citations/8350924 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8350924 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8350924 | http://www.w3.org/2000/01/rdf-schema#comment | "The growth suppression function of the retinoblastoma protein (Rb) is though to be mediated by Rb binding to cellular proteins. p48 is one of the major proteins that binds to a putative functional domain at the carboxy terminus of the Rb protein. Here we report the isolation of a full-length complementary DNA (RbAp48) encoding p48. Complex formation between p48 and Rb occurs in vitro and in vivo, and apparently involves direct interaction between the proteins. Like Rb, p48 is a ubiquitously expressed nuclear protein. RbAp48 share sequence homology with MSI1, a negative regulator of the Ras-cyclic AMP pathway in the yeast Saccharomyces cerevisiae. Furthermore, like MSI1, human RbAp48 suppresses the heat-shock sensitivity of the yeast ira1 strains and RAS2Val19 strains. Interaction with p48 may be one of the mechanisms for suppression of growth mediated by Rb."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.org/dc/terms/identifier | "doi:10.1038/364648a0"xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.org/dc/terms/identifier | "doi:10.1038/364648a0"xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/author | "Jones D."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/author | "Jones D."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/author | "Ling N."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/author | "Ling N."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/author | "Qian Y.-W."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/author | "Qian Y.-W."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/author | "Lee E.Y.-H.P."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/author | "Lee E.Y.-H.P."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/author | "Hollingsworth R.E. Jr."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/author | "Hollingsworth R.E. Jr."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/author | "Wang Y.-C.J."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/author | "Wang Y.-C.J."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/pages | "648-652"xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/pages | "648-652"xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/title | "A retinoblastoma-binding protein related to a negative regulator of Ras in yeast."xsd:string |
| http://purl.uniprot.org/citations/8350924 | http://purl.uniprot.org/core/title | "A retinoblastoma-binding protein related to a negative regulator of Ras in yeast."xsd:string |