http://purl.uniprot.org/citations/8378315 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8378315 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8378315 | http://www.w3.org/2000/01/rdf-schema#comment | "Interleukin 3 (IL-3) regulates the proliferation and differentiation of hematopoietic cells. Although the IL-3 receptor chains lack kinase catalytic domains, IL-3 induces tyrosine phosphorylation of cellular proteins. To investigate the potential role of the JAK family of protein-tyrosine kinases in IL-3 signal transduction, we have obtained full-length cDNA clones for murine Jak1 and Jak2 protein-tyrosine kinases and prepared antiserum against the predicted proteins. Using antisera against Jak2, we demonstrate that IL-3 stimulation results in the rapid and specific tyrosine phosphorylation of Jak2 and activates its in vitro kinase activity."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.90.18.8429"xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.90.18.8429"xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/author | "Yi T."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/author | "Yi T."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/author | "Witthuhn B.A."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/author | "Witthuhn B.A."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/author | "Cleveland J.L."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/author | "Cleveland J.L."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/author | "Silvennoinen O."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/author | "Silvennoinen O."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/author | "Ihle J.N."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/author | "Ihle J.N."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/author | "Quelle F.W."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/author | "Quelle F.W."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/pages | "8429-8433"xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/pages | "8429-8433"xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/title | "Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction."xsd:string |
http://purl.uniprot.org/citations/8378315 | http://purl.uniprot.org/core/title | "Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction."xsd:string |