| http://purl.uniprot.org/citations/8386827 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8386827 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8386827 | http://www.w3.org/2000/01/rdf-schema#comment | "We have cloned a 4.2-kb murine cDNA encoding the Tek receptor tyrosine kinase (RTK), which is expressed in endothelial cells and their progenitors. The 1122-residue protein contains an extracellular domain comprising three fibronectin type III repeats fused to two immunoglobulin-like loops that are in turn separated by three epidermal growth factor-like repeats. The association of these different structural motifs and their characteristic arrangement in the Tek extracellular domain has been reported for only one other RTK, Tie, an endothelial-specific RTK of human origin. We show here that Tek and Tie are encoded by distinct genes and that, together, these receptors define a new subfamily of RTKs. In addition, we demonstrate that the tek cDNA, when introduced into COS cells, encodes a product of 140 kDa and that this protein and/or tek transcripts are detectable in highly vascularized embryonic tissues and in some, but not all, cell lines of endothelial origin."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/author | "Fong G.-H."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/author | "Fong G.-H."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/author | "Dumont D.J."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/author | "Dumont D.J."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/author | "Breitman M.L."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/author | "Breitman M.L."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/author | "Auerbach R."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/author | "Auerbach R."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/author | "Gradwol G.J."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/author | "Gradwol G.J."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/pages | "1293-1301"xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/pages | "1293-1301"xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/title | "The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/title | "The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors."xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/volume | "8"xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://purl.uniprot.org/core/volume | "8"xsd:string |
| http://purl.uniprot.org/citations/8386827 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8386827 |
| http://purl.uniprot.org/citations/8386827 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8386827 |