| http://purl.uniprot.org/citations/8423800 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8423800 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8423800 | http://www.w3.org/2000/01/rdf-schema#comment | "Using an expression cDNA cloning approach, we examined human tumor cell lines for novel oncogenes that might evade detection by conventional techniques. We isolated a transforming sequence that was highly efficient in transforming NIH 3T3 mouse fibroblasts. DNA sequence analysis identified the gene as the human homolog of a recently cloned alpha subunit of mouse GTP-binding protein G alpha 12. NIH 3T3 cells transfected with G alpha 12 cDNA grew in soft agar and were tumorigenic in nude mice. There were no apparent mutations in the cloned cDNA in comparison with a G alpha 12 cDNA clone isolated from a normal human epithelial cell library, implying that overexpression alone was sufficient to cause NIH 3T3 cell transformation. The observed altered growth properties mediated by G alpha 12 showed a certain degree of dependency on serum factors, and its mitogenic potential was also potently inhibited by suramin treatment."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.13.2.762-768.1993"xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.13.2.762-768.1993"xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/author | "Miki T."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/author | "Miki T."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/author | "Aaronson S.A."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/author | "Aaronson S.A."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/author | "Chan A.M.-L."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/author | "Chan A.M.-L."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/author | "Fleming T.P."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/author | "Fleming T.P."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/author | "McGovern E.S."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/author | "McGovern E.S."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/author | "Chedid M."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/author | "Chedid M."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/name | "Mol. Cell. Biol."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/pages | "762-768"xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/pages | "762-768"xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/title | "Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product."xsd:string |
| http://purl.uniprot.org/citations/8423800 | http://purl.uniprot.org/core/title | "Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product."xsd:string |