| http://purl.uniprot.org/citations/8598453 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8598453 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8598453 | http://www.w3.org/2000/01/rdf-schema#comment | "FAS/Apo-1 (CD95) is an apoptosis-signaling cell surface receptor belonging to the TNF receptor family. Tumor cells resistant to Fas-mediated apoptosis have been described, but to date, the mechanisms responsible for this resistance are not well understood. We found that a series of apoptosis-resistant clones from human HUT78 lymphoma cells express a splicing variant coding for a truncated Fas molecule that lacks the intracellular death-signaling domain. The mutation responsible for the FasExo8Del expression was identified as a deletion-insertion in the intron 7/exon 8 region of the Fas gene. Moreover this mutation affects the phenotype in a dominant negative fashion, i.e., even in the presence of the normal receptor."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/author | "Testi R."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/author | "Testi R."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/author | "Cascino I."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/author | "Cascino I."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/author | "De Maria R."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/author | "De Maria R."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/author | "Papoff G."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/author | "Papoff G."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/author | "Ruberti G."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/author | "Ruberti G."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/name | "J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/name | "J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/pages | "13-17"xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/pages | "13-17"xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/title | "Fas/Apo-1 (CD95) receptor lacking the intracytoplasmic signaling domain protects tumor cells from Fas-mediated apoptosis."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/title | "Fas/Apo-1 (CD95) receptor lacking the intracytoplasmic signaling domain protects tumor cells from Fas-mediated apoptosis."xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/volume | "156"xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://purl.uniprot.org/core/volume | "156"xsd:string |
| http://purl.uniprot.org/citations/8598453 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8598453 |
| http://purl.uniprot.org/citations/8598453 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8598453 |