| http://purl.uniprot.org/citations/8649822 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8649822 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8649822 | http://www.w3.org/2000/01/rdf-schema#comment | "We describe the isolation of human LH-2, a putative transcription factor containing two cysteine-rich regions (LIM domains) and a homeobox (Hox) DNA-binding domain. High levels of hLH-2 expression were observed in all cases of chronic myelogenous leukaemia (CML) tested, regardless of disease status. hLH-2 was mapped to chromosome 9Q33-34.1, in the same region as the reciprocal translocation that creates the BCR-ABL chimera of the Philadelphia chromosome (Ph'), the hallmark of CML; hLH-2 was retained on the derivative 9 chromosome and is therefore centromeric of c-ABL. The proximity of hLH-2 to the breakpoint on chromosome 9 raises the possibility of cis-activation by the t(9;22)(q34;q11) translocation. In addition to finding hLH-2 expression in all cases of CML, expression was observed in lymphoid malignancies and myeloid cell lines, but not in primary cases of acute myelogenous leukaemia. The role of hLH-2 in the development or progression of leukaemia is not known. However, hLH-2 may prove useful as a marker of CML for monitoring residual disease."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Tsui L.-C."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Tsui L.-C."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Okuno Y."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Okuno Y."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Heng H.H.Q."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Heng H.H.Q."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Siderovski D.P."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Siderovski D.P."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Shi X.-M."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Shi X.-M."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Dong W.-F."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Dong W.-F."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Minden M.D."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Minden M.D."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Wu H.-K."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/author | "Wu H.-K."xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/name | "Oncogene"xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/pages | "1205-1212"xsd:string |
| http://purl.uniprot.org/citations/8649822 | http://purl.uniprot.org/core/pages | "1205-1212"xsd:string |