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http://purl.uniprot.org/citations/8684460http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8684460http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8684460http://www.w3.org/2000/01/rdf-schema#comment"The crystal structure of the human p27Kip1 kinase inhibitory domain bound to the phosphorylated cyclin A-cyclin-dependent kinase 2 (Cdk2) complex has been determined at 2.3 angstrom. p27Kip1 binds the complex as an extended structure interacting with both cyclin A and Cdk2. On cyclin A, it binds in a groove formed by conserved cyclin box residues. On Cdk2, it binds and rearranges the amino-terminal lobe and also inserts into the catalytic cleft, mimicking ATP."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.org/dc/terms/identifier"doi:10.1038/382325a0"xsd:string
http://purl.uniprot.org/citations/8684460http://purl.org/dc/terms/identifier"doi:10.1038/382325a0"xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/author"Jeffrey P.D."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/author"Jeffrey P.D."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/author"Pavletich N.P."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/author"Pavletich N.P."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/author"Massague J."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/author"Massague J."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/author"Russo A.A."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/author"Russo A.A."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/author"Patten A.K."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/author"Patten A.K."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/date"1996"xsd:gYear
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/name"Nature"xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/name"Nature"xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/pages"325-331"xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/pages"325-331"xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/title"Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/title"Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex."xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/volume"382"xsd:string
http://purl.uniprot.org/citations/8684460http://purl.uniprot.org/core/volume"382"xsd:string