http://purl.uniprot.org/citations/8706133 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8706133 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8706133 | http://www.w3.org/2000/01/rdf-schema#comment | "We describe the complete beta-tubulin folding pathway. Folding intermediates produced via ATP-dependent interaction with cytosolic chaperonin undergo a sequence of interactions with four proteins (cofactors A, D, E, and C). The postchaperonin steps in the reaction cascade do not depend on ATP or GTP hydrolysis, although GTP plays a structural role in tubulin folding. Cofactors A and D function by capturing and stabilizing beta-tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Sequence analysis identifies yeast homologs of cofactors D (cin1) and E (pac2), characterized by mutations that affect microtubule function."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)80100-2"xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)80100-2"xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/author | "Ampe C."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/author | "Ampe C."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/author | "Cowan N.J."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/author | "Cowan N.J."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/author | "Huang Y."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/author | "Huang Y."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/author | "Tian G."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/author | "Tian G."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/author | "Vandekerckhove J."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/author | "Vandekerckhove J."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/author | "Rommelaere H."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/author | "Rommelaere H."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/pages | "287-296"xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/pages | "287-296"xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/title | "Pathway leading to correctly folded beta-tubulin."xsd:string |
http://purl.uniprot.org/citations/8706133 | http://purl.uniprot.org/core/title | "Pathway leading to correctly folded beta-tubulin."xsd:string |