| http://purl.uniprot.org/citations/8751440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8751440 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8751440 | http://www.w3.org/2000/01/rdf-schema#comment | "Totipotent germline blastomeres in Caenorhabditis elegans contain, but do not respond to, factors that promote somatic differentiation in other embryonic cells. Mutations in the maternal gene pie-1 result in the germline blastomeres adopting somatic cell fates. Here we show that pie-1 encodes a nuclear protein, PIE-1, that is localized to the germline blastomeres throughout early development. During division of each germline blastomere, PIE-1 initially associates with both centrosomes of the mitotic spindle. However, PIE-1 rapidly disappears from the centrosome destined for the somatic daughter, and persists in the centrosome of the daughter that becomes the next germline blastomere. The PIE-1 protein contains potential zinc-finger motifs also found in the mammalian growth-factor response protein TIS-11/NUP475 (refs 4-7). The localization and genetic properties of pie-1 provide an example of a repressor-based mechanism for preserving pluripotency within a stem cell lineage."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.org/dc/terms/identifier | "doi:10.1038/382710a0"xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.org/dc/terms/identifier | "doi:10.1038/382710a0"xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/author | "Schubert C."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/author | "Schubert C."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/author | "Zhang W."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/author | "Zhang W."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/author | "Priess J.R."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/author | "Priess J.R."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/author | "Mello C.C."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/author | "Mello C.C."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/author | "Draper B."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/author | "Draper B."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/author | "Lobel R."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/author | "Lobel R."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/pages | "710-712"xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/pages | "710-712"xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/title | "The PIE-1 protein and germline specification in C. elegans embryos."xsd:string |
| http://purl.uniprot.org/citations/8751440 | http://purl.uniprot.org/core/title | "The PIE-1 protein and germline specification in C. elegans embryos."xsd:string |