http://purl.uniprot.org/citations/8790944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8790944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8790944 | http://www.w3.org/2000/01/rdf-schema#comment | "NCR-G3 cells were established from a testicular embryonal carcinoma and were differentiated into multi-lineages including trophectoderm cells by exposure to retinoic acid. The differentiated cells began to produce human chorionic gonadotropin (hCG), a trophectoderm-specific hormone, which was regulated at the mRNA level. As we assumed that genes responsible for differentiation were differentially expressed at the early stage of retinoic acid-induced differentiation, we prepared a cDNA library from retinoic acid-treated NCR-G3 cells. This cDNA library was then screened for genes whose expression was induced during the differentiation of these cells. From about 5 x 10(4) clones screened, three independent sequences were isolated. Sequencing analysis revealed that clone 1002 codes for mcl1/EAT, which has a Bcl-2 homology domain. The expression of mcl1/EAT, the Bcl-2 related gene, was increased at an early stage of the retinoic acid-induced differentiation and preceded the up-regulation of cytokeratin and hCG genes after ratinoic acid treatment. Furthermore, mcl1/EAT was also up-regulated by heat shock, which has recently been shown to induce the cells to differentiate."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.org/dc/terms/identifier | "doi:10.1247/csf.21.143"xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.org/dc/terms/identifier | "doi:10.1247/csf.21.143"xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/author | "Imai S."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/author | "Imai S."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/author | "Inazawa J."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/author | "Inazawa J."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/author | "Maruyama T."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/author | "Maruyama T."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/author | "Takano T."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/author | "Takano T."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/author | "Hata J."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/author | "Hata J."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/author | "Umezawa A."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/author | "Umezawa A."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/name | "Cell Struct. Funct."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/name | "Cell Struct. Funct."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/pages | "143-150"xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/pages | "143-150"xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/title | "Induction of mcl1/EAT, Bcl-2 related gene, by retinoic acid or heat shock in the human embryonal carcinoma cells, NCR-G3."xsd:string |
http://purl.uniprot.org/citations/8790944 | http://purl.uniprot.org/core/title | "Induction of mcl1/EAT, Bcl-2 related gene, by retinoic acid or heat shock in the human embryonal carcinoma cells, NCR-G3."xsd:string |