| http://purl.uniprot.org/citations/8797825 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8797825 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8797825 | http://www.w3.org/2000/01/rdf-schema#comment | "The transcription factor NF-kappa B regulates genes participating in immune and inflammatory responses. In T lymphocytes, NF-kappa B is sequestered in the cytosol by the inhibitor I kappa B-alpha and released after serine phosphorylation of I kappa B-alpha that regulates its ubiquitin-dependent degradation. We report an alternative mechanism of NF-kappa B activation. Stimulation of Jurkat T cells with the protein tyrosine phosphatase inhibitor and T cell activator pervanadate led to NF-kappa B activation through tyrosine phosphorylation but not degradation of I kappa B-alpha. Pervanadate-induced I kappa B-alpha phosphorylation and NF-kappa B activation required expression of the T cell tyrosine kinase p56ick. Reoxygenation of hypoxic cells appeared as a physiological effector of I kappa B-alpha tyrosine phosphorylation. Tyrosine phosphorylation of I kappa B-alpha represents a proteolysis-independent mechanism of NF-kappa B activation that directly couples NF-kappa B to cellular tyrosine kinase."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)80153-1"xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)80153-1"xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Mueller-Dieckmann C."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Mueller-Dieckmann C."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Auberger P."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Auberger P."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Pahl H.L."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Pahl H.L."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Baeuerle P.A."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Baeuerle P.A."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Rossi B."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Rossi B."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Farahifar D."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Farahifar D."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Imbert V."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Imbert V."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Livolsi A."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Livolsi A."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Peyron J.-F."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Peyron J.-F."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Rupec R.A."xsd:string |
| http://purl.uniprot.org/citations/8797825 | http://purl.uniprot.org/core/author | "Rupec R.A."xsd:string |