| http://purl.uniprot.org/citations/9027314 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9027314 | http://www.w3.org/2000/01/rdf-schema#comment | "Bcl-2 is an integral membrane protein located mainly on the outer membrane of mitochondria. Overexpression of Bcl-2 prevents cells from undergoing apoptosis in response to a variety of stimuli. Cytosolic cytochrome c is necessary for the initiation of the apoptotic program, suggesting a possible connection between Bcl-2 and cytochrome c, which is normally located in the mitochondrial intermembrane space. Cells undergoing apoptosis were found to have an elevation of cytochrome c in the cytosol and a corresponding decrease in the mitochondria. Overexpression of Bcl-2 prevented the efflux of cytochrome c from the mitochondria and the initiation of apoptosis. Thus, one possible role of Bcl-2 in prevention of apoptosis is to block cytochrome c release from mitochondria."xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.275.5303.1129"xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/author | "Liu X."xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/author | "Yang J."xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/author | "Wang X."xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/author | "Cai J."xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/author | "Jones D.P."xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/author | "Bhalla K."xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/author | "Kim C.N."xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/author | "Ibrado A.M."xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/author | "Peng T.I."xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/pages | "1129-1132"xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/title | "Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked."xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://purl.uniprot.org/core/volume | "275"xsd:string |
| http://purl.uniprot.org/citations/9027314 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9027314 |
| http://purl.uniprot.org/citations/9027314 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9027314 |
| http://purl.uniprot.org/uniprot/P10415#attribution-37FC926091CB1036BB3BF55F1415A213 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9027314 |
| http://purl.uniprot.org/uniprot/P10415#attribution-490A2323D7AC4E1EFDFBF6B3A70275F2 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9027314 |