| http://purl.uniprot.org/citations/9164944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9164944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9164944 | http://www.w3.org/2000/01/rdf-schema#comment | "We recently described a novel murine CXC chemokine, designated lipopolysaccharide-induced CXC chemokine (LIX). In an ongoing search for new human chemokines related to LIX, we cloned the gene for human granulocyte chemotactic protein-2 (GCP-2) as well as previously described CXC chemokine genes, including epithelial cell-derived neutrophil-activating peptide-78 (ENA-78). Both coding and noncoding portions of the GCP-2 gene have very high nucleotide similarity to ENA-78, except for the occurrence of a long interspersed DNA-1 sequence 5' of the GCP-2 gene. The GCP-2 gene encodes a propeptide of 114 amino acid residues. The predicted 77-residue mature peptide is identical with the GCP-2 protein previously isolated from MG-63 osteosarcoma cells, except for two additional residues at the carboxyl terminus. We confirmed expression of the gene by Northern analysis and by cloning a portion of the cDNA from reverse transcribed MG-63 cell RNA. Despite 85% identity of the first 270 nucleotides 5' of the transcription start sites, GCP-2 and ENA-78 show cell-specific differences in regulation. GCP-2 is induced in MG-63, but not A549 cells by TNF-alpha, IL-1beta, and LPS, while ENA-78 is expressed in both cell types. Analysis of nucleotide sequence relationships does not support the proposal, by others, that LIX is murine GCP-2. LIX is no more closely related to human GCP-2 than to human ENA-78 and is more distant from both human genes than is porcine alveolar macrophage chemotactic factor-II."xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/author | "Herschman H.R."xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/author | "Herschman H.R."xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/author | "Smith J.B."xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/author | "Smith J.B."xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/author | "Rovai L.E."xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/author | "Rovai L.E."xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/name | "J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/name | "J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/pages | "5257-5266"xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/pages | "5257-5266"xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/title | "Cloning and characterization of the human granulocyte chemotactic protein-2 gene."xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/title | "Cloning and characterization of the human granulocyte chemotactic protein-2 gene."xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/volume | "158"xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://purl.uniprot.org/core/volume | "158"xsd:string |
| http://purl.uniprot.org/citations/9164944 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9164944 |
| http://purl.uniprot.org/citations/9164944 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9164944 |
| http://purl.uniprot.org/citations/9164944 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9164944 |
| http://purl.uniprot.org/citations/9164944 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9164944 |
| http://purl.uniprot.org/uniprot/P80162 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/9164944 |
| http://purl.uniprot.org/uniprot/O00172 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/9164944 |