http://purl.uniprot.org/citations/9207182 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9207182 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9207182 | http://www.w3.org/2000/01/rdf-schema#comment | "We have identified a human Eph-family protein, HEP, gene located in human chromosomal region 7q33-->q35. The deduced amino acid sequence shared primary structural properties of Eph-family receptor tyrosine kinases. However, six invariant amino acids such as a lysine in the ATP-binding site and an aspartic acid in the phosphotransfer site of a conserved catalytic domain were substituted with other amino acid residues in HEP. Thus, no intrinsic tyrosine kinase activity was detectable in the catalytic domain expressed in CHO-K1 cell transfectants. Although most kinase-defective mutants of growth factor receptors have been reported as pathogenic receptors, its transcript was abundantly expressed in normal human adult tissues. A 135-kDa HEP protein was expressed in the human brain as much as in CHO-K1 cells transfected with a HEP cDNA expression vector. HEP is the first description of a kinase-defective Eph-family protein expressed abundantly in normal human tissues."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1997.6812"xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1997.6812"xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Ito M."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Ito M."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Matsuoka H."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Matsuoka H."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Iwata N."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Iwata N."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Matsui T."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Matsui T."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Nagata A."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Nagata A."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Chihara K."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Chihara K."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Takai S."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Takai S."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Shimoyama M."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/author | "Shimoyama M."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/9207182 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |