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http://purl.uniprot.org/citations/9228018http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9228018http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9228018http://www.w3.org/2000/01/rdf-schema#comment"We identified and cloned a novel human protein that contains FADD/Mort1 death effector domain homology regions, designated FLAME-1. FLAME-1, although most similar in structure to Mch4 and Mch5, does not possess caspase activity but can interact specifically with FADD, Mch4, and Mch5. Interestingly, FLAME-1 is recruited to the Fas receptor complex and can abrogate Fas/TNFR-induced apoptosis upon expression in FasL/tumor necrosis factor-sensitive MCF-7 cells, possibly by acting as a dominant-negative inhibitor. These findings identify a novel endogenous control point that regulates Fas/TNFR1-mediated apoptosis."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.org/dc/terms/identifier"doi:10.1074/jbc.272.30.18542"xsd:string
http://purl.uniprot.org/citations/9228018http://purl.org/dc/terms/identifier"doi:10.1074/jbc.272.30.18542"xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Wang Y."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Wang Y."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Alnemri E.S."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Alnemri E.S."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Armstrong R.C."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Armstrong R.C."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Banks S."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Banks S."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Ottilie S."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Ottilie S."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Tomaselli K.J."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Tomaselli K.J."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Croce C.M."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Croce C.M."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Fernandes-Alnemri T."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Fernandes-Alnemri T."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Ahmad M."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Ahmad M."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Srinivasula S.M."xsd:string
http://purl.uniprot.org/citations/9228018http://purl.uniprot.org/core/author"Srinivasula S.M."xsd:string