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http://purl.uniprot.org/citations/9311921http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9311921http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9311921http://www.w3.org/2000/01/rdf-schema#comment"Activation of the nuclear factor of activated T cells transcription factor (NF-AT) is a key event underlying lymphocyte action. The CAML (calcium-modulator and cyclophilin ligand) protein is a coinducer of NF-AT activation when overexpressed in Jurkat T cells. A member of the tumor necrosis factor receptor superfamily was isolated by virtue of its affinity for CAML. Cross-linking of this lymphocyte-specific protein, designated TACI (transmembrane activator and CAML-interactor), on the surface of transfected Jurkat cells with TACI-specific antibodies led to activation of the transcription factors NF-AT, AP-1, and NFkappaB. TACI-induced activation of NF-AT was specifically blocked by a dominant-negative CAML mutant, thus implicating CAML as a signaling intermediate."xsd:string
http://purl.uniprot.org/citations/9311921http://purl.org/dc/terms/identifier"doi:10.1126/science.278.5335.138"xsd:string
http://purl.uniprot.org/citations/9311921http://purl.org/dc/terms/identifier"doi:10.1126/science.278.5335.138"xsd:string
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/author"Bram R.J."xsd:string
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/author"Bram R.J."xsd:string
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/author"von Buelow G.-U."xsd:string
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/author"von Buelow G.-U."xsd:string
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/pages"138-141"xsd:string
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/pages"138-141"xsd:string
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/title"NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily."xsd:string
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/title"NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily."xsd:string
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/volume"278"xsd:string
http://purl.uniprot.org/citations/9311921http://purl.uniprot.org/core/volume"278"xsd:string
http://purl.uniprot.org/citations/9311921http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9311921
http://purl.uniprot.org/citations/9311921http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9311921
http://purl.uniprot.org/citations/9311921http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9311921
http://purl.uniprot.org/citations/9311921http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9311921
http://purl.uniprot.org/uniprot/P49069http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/9311921
http://purl.uniprot.org/uniprot/O14836http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/9311921