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http://purl.uniprot.org/citations/9344668http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9344668http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9344668http://www.w3.org/2000/01/rdf-schema#comment"Phosphodiesterase I (EC 3.1.4.1)/nucleotide pyrophosphatase (EC 3.6.1.9) enzymes are a family of type II transmembrane proteins that catalyze the cleavage of phosphodiester and phosphosulfate bonds of a variety of molecules, including deoxynucleotides, NAD, and nucleotide sugars. The human genes for two members of this family have been cloned and designated PC-1 (PDNP1) and PD-Ialpha/autotaxin (PDNP2). We have now cloned the third member of this family from a human prostate cDNA library and designated it human phosphodiesterase-Ibeta (PD-Ibeta). The PD-Ibeta cDNA contains a 2625-bp-long open reading frame which encodes an 875-amino-acid protein. COS-7 cells transfected with an expression vector, pBK-CMV, containing PD-Ibeta cDNA had high phosphodiesterase I activity compared to the mock-transfected cells. By using in situ hybridization to human metaphase chromosomes, we have assigned the locus for the PD-Ibeta (PDNP3) gene to the q22 region of human chromosome 6."xsd:string
http://purl.uniprot.org/citations/9344668http://purl.org/dc/terms/identifier"doi:10.1006/geno.1997.4949"xsd:string
http://purl.uniprot.org/citations/9344668http://purl.org/dc/terms/identifier"doi:10.1006/geno.1997.4949"xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/author"Nakamura H."xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/author"Nakamura H."xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/author"Sano K."xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/author"Sano K."xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/author"Goding J.W."xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/author"Goding J.W."xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/author"Piao J.-H."xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/author"Piao J.-H."xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/author"Jin-Hua P."xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/name"Genomics"xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/name"Genomics"xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/pages"412-415"xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/pages"412-415"xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/title"Molecular cloning and chromosomal localization of PD-Ibeta (PDNP3), a new member of the human phosphodiesterase I genes."xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/title"Molecular cloning and chromosomal localization of PD-Ibeta (PDNP3), a new member of the human phosphodiesterase I genes."xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/volume"45"xsd:string
http://purl.uniprot.org/citations/9344668http://purl.uniprot.org/core/volume"45"xsd:string
http://purl.uniprot.org/citations/9344668http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9344668