| http://purl.uniprot.org/citations/9371819 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9371819 | http://www.w3.org/2000/01/rdf-schema#comment | "Asthma is a complex heritable inflammatory disorder of the airways associated with clinical signs of atopy and bronchial hyperresponsiveness. Recent studies localized a major gene for asthma to chromosome 5q31-q33 in humans. Thus, this segment of the genome represents a candidate region for genes that determine susceptibility to bronchial hyperresponsiveness and atopy in animal models. Homologs of candidate genes on human chromosome 5q31-q33 are found in four regions in the mouse genome, two on chromosome 18, and one each on chromosomes 11 and 13. We assessed bronchial responsiveness as a quantitative trait in mice and found it linked to chromosome 13. Interleukin 9 (IL-9) is located in the linked region and was analyzed as a gene candidate. The expression of IL-9 was markedly reduced in bronchial hyporesponsive mice, and the level of expression was determined by sequences within the qualitative trait locus (QTL). These data suggest a role for IL-9 in the complex pathogenesis of bronchial hyperresponsiveness as a risk factor for asthma."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.94.24.13175"xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Zhang L.Y."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Grasso L."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Zhou T."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Buetow K.H."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Nicolaides N.C."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Levitt R.C."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Kleeberger S.R."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Ewart S.L."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Dragwa C.R."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Eleff S.M."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Holroyd K.J."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Kiser M.B."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Messler C.J."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/author | "Sullivan C.D."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/pages | "13175-13180"xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/title | "Interleukin 9: a candidate gene for asthma."xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://purl.uniprot.org/core/volume | "94"xsd:string |
| http://purl.uniprot.org/citations/9371819 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9371819 |
| http://purl.uniprot.org/citations/9371819 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9371819 |
| http://purl.uniprot.org/uniprot/P15248#attribution-9796514DA1543FE0CFFB7B0DA34C7F62 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9371819 |