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http://purl.uniprot.org/citations/9473496http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9473496http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9473496http://www.w3.org/2000/01/rdf-schema#comment"We have isolated cDNA encoding a novel member (207 amino acids) of the FGF family from the rat heart by homology-based polymerase chain reaction. As this protein is the 16th documented member of the FGF family, we tentatively term it FGF-16. Among FGF family members, FGF-16 is most similar (73% amino acid identity) to FGF-9. We have also determined the structure of human FGF-16 with high amino acid sequence identity (98.6%) to rat FGF-16. Although the predicted FGF-16 amino acid sequence lacks a typical signal sequence, recombinant rat FGF-16 was efficiently secreted by Sf9 insect cells infected with recombinant baculovirus containing the cDNA. FGF-16 mRNA was predominantly expressed in the rat heart among the adult major tissues examined. The expression profile of FGF-16 mRNA was quite different from those of other members of the FGF family. In rat embryos, FGF-16 mRNA was predominantly expressed in the brown adipose tissue. However, the expression decreased greatly after birth. These results indicate that FGF-16 in embryos might play a role in development of the brown adipose tissue."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.1998.8073"xsd:string
http://purl.uniprot.org/citations/9473496http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.1998.8073"xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Arakawa T."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Arakawa T."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Itoh N."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Itoh N."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Mikami T."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Mikami T."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Ozaki K."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Ozaki K."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Yamamoto S."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Yamamoto S."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Miyake A."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Miyake A."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Konishi M."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Konishi M."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Hernday N.A."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Hernday N.A."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Martin F.H."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/author"Martin F.H."xsd:string
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9473496http://purl.uniprot.org/core/date"1998"xsd:gYear